The evidence's certainty was assessed as ranging from low to moderate. There was a connection between a higher legume intake and lower mortality rates for all causes and stroke, but no relationship was detected for cardiovascular disease, coronary heart disease, and cancer mortality. These findings are in agreement with dietary recommendations emphasizing a higher intake of legumes.
Although a considerable amount of data exists on the correlation between diet and cardiovascular mortality, research on long-term food group intake, with the potential for cumulative effects on long-term cardiovascular health, is comparatively scant. This study, therefore, investigated the connection between the long-term use of 10 food groups and death due to cardiovascular disease. In our systematic quest, Medline, Embase, Scopus, CINAHL, and Web of Science were searched for relevant data up to January 2022. A total of 22 studies, involving 70,273 participants who had experienced cardiovascular mortality, were selected from the initial 5,318 studies. Hazard ratios and 95% confidence intervals were determined through the use of a random effects model for summary statistics. A sustained high consumption of whole grains (HR 0.87; 95% CI 0.80 to 0.95; P = 0.0001), fruits and vegetables (HR 0.72; 95% CI 0.61 to 0.85; P < 0.00001), and nuts (HR 0.73; 95% CI 0.66 to 0.81; P < 0.000001) was found to substantially decrease cardiovascular mortality. Every 10 grams more of whole grains consumed daily was associated with a 4% lower risk of cardiovascular mortality; conversely, every 10-gram rise in red/processed meat intake per day was linked to an 18% higher risk of cardiovascular mortality. combined remediation Compared to the lowest red/processed meat intake group, the highest consumption group showed a notable increase in the risk of cardiovascular mortality (Hazard Ratio 1.23; 95% Confidence Interval 1.09 to 1.39; P = 0.0006). There was no link between cardiovascular mortality and high consumption of dairy products (HR 111; 95% CI 092, 134; P = 028), as well as consumption of legumes (HR 086; 95% CI 053, 138; P = 053). The dose-response study indicated a 0.5% reduction in cardiovascular mortality for every 10-gram increment in weekly legume intake. High and consistent consumption of whole grains, vegetables, fruits, and nuts, while simultaneously having a low intake of red/processed meat, appears linked to a lower occurrence of cardiovascular mortality, according to our conclusions. Additional studies exploring the long-term relationship between legume consumption and cardiovascular mortality are encouraged. AS601245 The registration of this research at PROSPERO is CRD42020214679.
A rise in the popularity of plant-based diets has occurred recently, positioning them as a dietary strategy associated with reducing the risk of chronic diseases. Despite this, the manner in which PBDs are classified differs based on the type of diet consumed. Some processed foods, often labeled PBDs, exhibit healthful properties due to a high content of vitamins, minerals, antioxidants, and fiber, but conversely, others are classified as unhealthful due to their high simple sugar and saturated fat content. The protective effect of a PBD on diseases is greatly affected by its category or classification. Metabolic syndrome (MetS), encompassing elevated plasma triglycerides and reduced HDL cholesterol, alongside impaired glucose regulation, heightened blood pressure, and increased inflammatory markers, further contributes to a heightened risk of heart disease and diabetes. Therefore, a diet primarily consisting of plants might prove beneficial for those experiencing Metabolic Syndrome. We analyze plant-based dietary styles, including vegan, lacto-vegetarian, lacto-ovo-vegetarian, and pescatarian approaches, with a focus on how specific dietary elements affect weight management, dyslipidemia avoidance, insulin resistance prevention, hypertension management, and mitigating the impact of low-grade inflammation.
Grain-derived carbohydrates are prominently found in bread throughout the world. Individuals who ingest high levels of refined grains, with their low dietary fiber and high glycemic index, are at a greater risk of developing type 2 diabetes mellitus (T2DM) and other chronic diseases. Consequently, enhancements in the formulation of bread products might have implications for public health. A systematic review examined how regularly consuming reformulated breads influenced blood sugar levels in healthy adults, adults at risk for cardiometabolic issues, and those with type 2 diabetes. A literature review was carried out, employing MEDLINE, Embase, Web of Science, and the Cochrane Central Register of Controlled Trials databases. A two-week bread intervention was a component of the eligible studies which focused on adults, classified as healthy, with elevated cardiometabolic risk, or with diagnosed type 2 diabetes, and these studies detailed the glycemic outcomes: fasting blood glucose, fasting insulin, HOMA-IR, HbA1c, and postprandial glucose responses. Treatment effects, calculated using a random-effects model and generic inverse variance method, were expressed as mean differences (MD) or standardized mean differences (SMD) with 95% confidence intervals, combining the data. Of the studies examined, 22 met the inclusion criteria, encompassing 1037 participants. Intervention breads, modified from standard or comparative loaves, showed lower fasting blood glucose (MD -0.21 mmol/L; 95% CI -0.38, -0.03; I2 = 88%, moderate certainty of evidence), but no change in fasting insulin (MD -1.59 pmol/L; 95% CI -5.78, 2.59; I2 = 38%, moderate certainty of evidence), HOMA-IR (MD -0.09; 95% CI -0.35, 0.23; I2 = 60%, moderate certainty of evidence), HbA1c (MD -0.14; 95% CI -0.39, 0.10; I2 = 56%, very low certainty of evidence), or postprandial glucose (SMD -0.46; 95% CI -1.28, 0.36; I2 = 74%, low certainty of evidence). Subgroup analyses concerning fasting blood glucose levels showed a positive outcome primarily within the T2DM population, however, the evidence supporting this pattern is not highly conclusive. Our research indicates that reformulated breads, containing higher levels of dietary fiber, whole grains, and/or functional ingredients, have a positive impact on fasting blood glucose control in adults, specifically those with type 2 diabetes. The trial's entry in the PROSPERO registry is identified by the registration code CRD42020205458.
Food fermentation with sourdough—a collective of lactic bacteria and yeasts—is now widely seen by the public as a naturally occurring method for enhancing nutrition; nevertheless, the scientific basis for these claimed advantages remains uncertain. Through a systematic review, this study investigated the clinical evidence regarding sourdough bread's impact on health parameters. Bibliographic searches were performed across two databases, The Lens and PubMed, up to and including February 2022. Eligible studies were comprised of randomized controlled trials; these trials involved adults, both healthy and unhealthy, given either sourdough or yeast bread. From a total of 573 retrieved and examined articles, 25 clinical trials were deemed suitable for further investigation. biomarker screening In the 25 clinical trials, 542 individuals were involved. In the studies analyzed, the main outcomes under scrutiny were glucose response (N = 15), appetite (N = 3), gastrointestinal markers (N = 5), and cardiovascular markers (N = 2). In evaluating the health advantages of sourdough against other breads, a clear consensus proves elusive. This uncertainty stems from the interplay of several variables, including the microbial communities in the sourdough, the fermentation techniques used, the type of cereal, and the flour type, all of which can affect the nutritional value of the bread. Yet, research utilizing particular yeast strains and fermentation conditions saw substantial improvements in metrics linked to glucose management, feelings of fullness, and gastrointestinal comfort after the ingestion of bread. The reviewed information suggests sourdough holds significant potential to create diverse functional foods, but its complex and ever-shifting microbial community needs more standardized processes to fully confirm its clinical health effects.
Hispanic/Latinx households in the United States, particularly those with young children, have been disproportionately affected by food insecurity. Although the literature has shown evidence of a connection between food insecurity and adverse health effects in young children, the social determinants and related risk factors of food insecurity, especially within Hispanic/Latinx households with children under three, require further investigation to address this important vulnerability. A narrative review, structured by the Socio-Ecological Model (SEM), investigated the contributing factors of food insecurity among Hispanic/Latinx families with children under three. Employing PubMed, and four other search engines, a comprehensive literature search was carried out. Inclusion criteria were defined by English-language articles, published from November 1996 through May 2022, that investigated food insecurity in Hispanic/Latinx households containing children younger than three years. In the article review process, studies not situated in the United States, or those specifically examining refugees and temporary migrant workers were removed. The final articles (n = 27) yielded data on objective factors, settings, populations, study designs, food insecurity measurements, and results. An examination of the strength of evidence in each article was also performed. This research indicated an association between the food security of this population and several contributing factors, ranging from individual traits (e.g., intergenerational poverty, education) to interpersonal interactions (e.g., social support), organizational structures (e.g., interagency collaborations), community environments (e.g., food access), and public policies (e.g., nutritional programs, benefit caps). Considering all articles, a considerable percentage achieved a medium or high quality rating in terms of evidence strength, and these articles often centered on individual or policy considerations.